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When hydrophilic molecules are converted into hydrophobic substances through specific treatments, their ordered aggregation rate increases, thereby enhancing self-assembly efficiency

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They are produced by mast cells (LTC4), eosinophils, and basophils upon allergen challenge and act on CysLT1 receptors on airway smooth muscle to cause sustained bronchoconstriction that is not relieved by antihistamines but is blocked by leukotriene receptor antagonists such as montelukast

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