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Description
Colon refers to large intestine

The FDA then publishes these lists in the Purple Book database

However, the safety and side effect profile of most phytochemicals for AR is still unclear

10.1172/jci32561 [DOI] [PMC free article] [PubMed] [Google Scholar] 71

Investigator-assessed improvement Finding: The blinded investigator assessed the active treatment group as showing Scale 1 improvement (2650% improvement) at the final visit, while the placebo group showed Scale 0 improvement (025%)
This could enable larger trials with consistent evaluation at lower cost
