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This pathway regulates the expression of antioxidant and detoxifying enzymes [5,132,133]

doi: 10.1016/j.intimp.2019.01.022
In this respect, some endogenous thiol compounds, including cysteine, DHLA, and GSH, have attracted the interest of scientists for the treatment and prevention of COVID-19 due to their potent antioxidant, anti-inflammatory, and antiviral properties [130]

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Gerhard, A

Checkpoint activation: Simultaneously, IGF-1 enhances PD-L1 expression through IGF-1R-dependent activation of AKT and ERK pathways, reinforcing an immune-evasive tumor phenotype
