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doi:10.1016/j.dsx.2020.01.002 Santos HO, da Silva GAR

Restores and promotes glutathione synthesis

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T., Kanat-Pektas M., Tuncer N., et al

Risk assessments for human inhalation toxicity based on traditional animal studies generally include a safety factor of 25 to account for uncertainties related to interspecies (animal-to-human: 2.5-safety factor) and inter-individual (human-to-human: 10-safety factor) variabilities ( in vitro PoDs from MucilAir readouts (i.e., TEER, lactate dehydrogenase leakage and resazurin metabolism analyses) with dosimetry information obtained from a computational fluid-particle dynamics (CFPD) model (Ramanarayanan et al., 2022)