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doi: 10.1210/jcem-42-1-197

These micro-clots physically impair capillary blood flow, preventing adequate oxygen and nutrient delivery to skeletal muscles and the brain during exertion
Increased reactive oxygen species production during reductive stress: the roles of mitochondrial glutathione and thioredoxin reductases

Similarly, inhibition of SL synthesis in Drosophila melanogaster impairs ISCs proliferation, highlighting that SL are key drivers of progenitor cell proliferation and gut regeneration 78
