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Hypomagnesemia is a commonly reported side effect of proton pump inhibitors (PPIs), a first-line treatment for gastric acid-related disorders

The two approaches are complementary, not competing

Less than 1% per year before the age of 65 to 6% per year beyond the age of 85 are the apparent age-specific incidence increases

In summary, FR activation has broad effects on molecular processes at the cell membrane, in the cytosol, and in the nucleus
doi: 10.1007/s00467-005-2085-4

Qian et al., 2023
