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[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Phillips C.M., Zatarain J.R., Nicholls M.E., Porter C., Widen S.G., Thanki K., Johnson P., Jawad M.U., Moyer M.P., Randall J.W., et al

It may reduce the absorption of oral medications by interacting with intestinal transporters, potentially affecting the bioavailability of drugs like metformin

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Moreover, Hcy upregulates the level of platelet-derived growth factors (PDGF) in ECs via DNA demethylation, thereby mediating the cross-talk between ECs and VSMCs and leading to VSMCs activation via MMPs upregulation [79]

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(B) The relationship between Trx system expression and treatment response in ICB-treated mouse model based on the TISMO database
