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used RSL3 to induce macrophage ferroptosis in vitro and investigated the effects of Qing Xin Xie Du Granule on ferroptosis in ApoE / mice

The trans-sulfuration pathway coupled with Met metabolism is highly active in hepatocytes and in other cells, which must meet the demand for Cys

[PubMed] [Google Scholar] 265.Vincenzi B., Santini D., Frezza A.M., Berti P., Vespasiani U., Picardi A., Tonini G

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IFN- disrupts energy expenditure and metabolic homeostasis in chronic inflammation of skeletal muscle cells by inducing HIC1 and transcriptional modulator class II transactivator (CIITA) (113)

The reason for this is that the glutathione in many foods is broken down in the gut and poorly absorbed