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Cysteine deficiency, a critical component of GSH, leads to mitochondrial membrane hyperpolarization and the accumulation of LOOH, thereby triggering iron-dependent cell death

Koochekpour, S., Majumdar, S., Azabdaftari, G., Attwood, K., Scioneaux, R., Subramani, D

doi:10.1016/j.copbio.2005.04.008

Accumulation of kynurenic acid, accompanied by reduced de novo NAD + synthesis, has a negative effect on mitochondrial function in liver resident T-cells which impairs their anti-tumor activity

I look forward to my second shot now and being even more powerful against the Rona and as Im walking to the backyard to drink my coffee I catch myself whistling I Got You Babe

This implies that extended periods of folate supplementation potentially have negative effects on the gut microbiome composition