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Description
Added complexity may not yield measurable additional benefit

Breast tenderness

What they did: A Phase 1 clinical trial in Croatia in the 1990s2000s
Ipratropium is a quaternary analog of atropine that when inhaled can antagonize the effects of heightened cholinergic tone on bronchial smooth muscle and mucus secretion, a condition most commonly associated with severe (vs mild) asthma

Its more common among people with a family history of the condition
Researchers first isolated it from epithalamin, a substance extracted from the pineal gland
