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Key Takeaways Metformin can interfere with vitamin B12 absorption, leading to deficiency in up to 41% of long-term users

Dr Anderson holds a NHMRC Senior Investigator Fellowship and reports grant funding from NHMRC, MRC, Penumbra, Takeda China and compensation from AstraZeneca Australia for consultant services

Side effects are most common when you first start using the medication or increase the dose, and higher doses of both drugs can lead to a higher risk of side effects

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