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Description
While preclinical data are compelling, clinical translation remains limited by small sample sizes, heterogeneity in endpoints, and variations in compound standardization

The degradation process involves multiple pathways including hydrolysis, oxidation, deamidation, and aggregation

A.BlainM.NadeauM.PatelB.AlvarezJ

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LvJ-MLS-QLiuZ-PZhangJGaoB-XYaoZ-Yet alConformational folding and disulfide bonding drive distinct stages of protein structure formation
doi: 10.1007/s11302-005-5435-6
