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This could be at least in part due to direct inhibition of cGMP phosphodiesterase (PDE5) activity, leading to an increase in the half-life of cGMP [170]
It binds the MC1R receptor, which sits on immune cells, gut lining cells, and skin cells
[DOI] [PubMed] [Google Scholar] 36.Anderson PM, Ramsay NK, Shu XO, Rydholm N, Rogosheske J, Nicklow R, et al
Although experimental studies have been highly instrumental in shedding novel information on aspects involved in MeHg-induced neurotoxicity, further research on the role of microglial cells and neuroinflammation, as well as potential therapeutic/antidotal strategies is warranted
J Agric Food Chem 2015;63:723624
[ foodchem.2007.08.085]
