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Biology of mitochondria in neurodegenerative diseases

doi: 10.1007/s00210-022-02372-7 164 JiangQXuNaKongLWangMLeiH

Further, inhibited actions of TNF result in the downregulated production of pro-inflammatory cytokines like IL-1and IL-6, decreased migration of leukocytes and lymphocytes to the inflammatory sites, initiation of apoptotic cascade in TNF-producing cells, including activated T cells and monocytes, enhanced concentration of NF-B inhibitor, and downregulated levels of acute phase proteins and endothelial adhesion molecules [158]

Creery D, Angel JB, Aucoin S, Weiss W, Cameron WD, Diaz-Mitoma F, Kumar A: Nef protein of human immunodeficiency virus and lipopolysaccharide induce expression of CD14 on human monocytes through differential utilization of interleukin-10

Targeted disruption of the CREM gene blocks the differentiation program in the first step of spermiogenesis