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( e ) FT282-CCNE1 cells transduced with shRNA targeting CrAT, CrOT, or TMLHE (shTMLHE) were incubated with 13 C 6 -glucose, and glucose-derived M + 2 acetyl-CoA was assessed (n = 8 technical replicates representative from 2 independent experiments)

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Metabolic engineering to improve provision of the precursor metabolites L-lysine and S -adenosyL-methionine (SAM) may increase de novo production of L-carnitine by the E

receiving equipment support grant in kind for federally funded study from MagVenture Inc and Neuronetics Inc

L-carnitine enhances resistance to oxidative stress by reducing DNA damage in Ataxia telangiectasia