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All information pertains to preclinical or published human trial data
Many clinics use weekly or twice-weekly patterns, but protocols vary
In brief, the peak area of the metabolite was normalized to the peak area of an isotopically labelled internal standard with similar elution time, both in samples from culture medium and external standard library dilutions
10.3389/fgene.2019.00308 129 WuK
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Chen JW, Ledet T, Orskov H et al (2003) A highly sensitive and specific assay for determination of IGF-I bioactivity in human serum
