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[DOI] [PMC free article] [PubMed] [Google Scholar] 158.Chen L, Sutharsan R, Lee JL, Cruz E, Asnicar B, Palliyaguru T, Wasielewska JM, Gaudin A, Song J, Leinenga G, Gtz J

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Analysis of metabolic self-inhibition based on the enzymological data obtained through a century of experimentation results collected in metabolism databases such as BRENDA [171] has shown a major role of metabolites as regulators of enzyme functions [172]