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Later, in 2022, they reported that intracellular copper build-up causes mitochondrial lipoylated protein oligomerization and destabilizes FeS cluster proteins, resulting in cuproptosis, an independent mode of cell death that is different from other RCD pathways (Ge et al., 2022)

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Uspenski Iu, P., et al., [Device laboratory and postmortem parallels in alcoholic hepatitis during combined therapy using thioctic (alpha-lipoic) acid]

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