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This article reports what has been documented, not what should be done

The efficacy of adjunctive N-acetylcysteine in major depressive disorder: a double-blind, randomized, placebo-controlled trial

Several NADs have entered the clinical trial recently, and some have been approved for therapeutic use in different fields

doi: 10.1089/ars.2007.1716

doi:10.1155/2012/190309 Slucca M, Harmon JS, Oseid EA, Bryan J, Robertson RP (2010) ATP-sensitive K + channel mediates the zinc switch-off signal for glucagon response during glucose deprivation

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