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doi: 10.1016/j.bpa.2013.06.009
Timelines vary significantly

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His research highlights three key tissues as fundamental components in mammalian aging and longevity regulation: the hypothalamus (serving as the central control hub), skeletal muscle (functioning as an effector), and adipose tissue (acting as a modulator)

Commonly associated with recovery, tissue repair and connective tissue research

PMID 29669618