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Jafari-Vayghan H, Varshosaz P, Hajizadeh-Sharafabad F, Razmi HR, Amirpour M, Tavakoli-Rouzbehani OM, et al

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

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MyD88 acts as a downstream signaling adaptor for all TLRs except TLR-3 ( Previous studies in mammals described several additional secondary signals, including plasma membrane disruption for bacterial toxins, lysosome destabilization, and liposome-triggering mitochondrial reactive oxygen species (ROS), leading to inflammasome oligomerization and activation (56)

Surg 2004