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However, it is noteworthy that the senescent phenotype of RA FLS highly expresses CDKN2A and releases more pro-inflammatory mediators in response to TNF or oxidative stress stimuli to promote inflammation (87)

2010 study by Leyh et al

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We also recommend treatment for any patient with an elevated alanine aminotransferase concentration and a history of ingesting more than 4 g of acetaminophen per day

Finally, the sections were counterstained with hematoxylin, dehydrated, and mounted with a coverslip