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In addition to oral l-carnitine, metformin was administered either intraperitoneally (ip, solubilized in 0.9% NaCl) at a concentration of 100 mg/kg of rat weight twice a day for 4 weeks in the l-carnitine + Metformin group [28]

10.1016/j.mam.2017.11.008 51 KnipeR

Brain Health and Mood: Acetyl-L-carnitine may improve cognitive function and reduce depression symptoms, comparable to some antidepressants in small studies

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However, the specific role of carnitine, a key molecule involved in lipid metabolism, in these metabolic alterations remains inadequately explored

Proc Natl Acad Sci U S A 104:1201712022