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The resulting decrease in IB levels allows NF-B to translocate into the nucleus

CrossRef Temporal change in the diagnosis and treatment rates of osteoporosis: results from the Korea National Health and Nutrition Examination Survey Y

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In Vivo Mouse Experiment Eight week old female athymic nude mice were purchased from Jackson Laboratories (cat# 002109)

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The specific mechanisms of action lie in the formation of hydrogen bonds between CGA and lipase, hydrophobic interactions between tryptophan (Trp) near the benzene ring and acyl binding bag, and weak interactions, such as van der Waals forces with surrounding amino acid residues, which together competitively inhibit the binding sites of endogenous lipase and lipoxygenase (LOX) (109)