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Along with this, the University of Pittsburgh Center for Research Computing, RRID: SCR 022735, has supported our work

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[PMC free article: PMC6276717] [PubMed: 29329447] 133

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[DOI] [Google Scholar] 49.Yang G., Chen Q., Wen D., Chen Z., Wang J., Chen G., Wang Z., Zhang X., Zhang Y., Hu Q., et al

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Use amber or opaque vials to block UV light exposure, which catalyzes oxidation and can degrade potency by 2030% within 72 hours under fluorescent or sunlight

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When stimulated, p65/p50 can be activated and transferred to the nucleus to regulate the transcription of various downstream inflammatory factors [25, 26]

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Nevertheless, future research should focus on examining temporal relationships between HPA axis function and immune-inflammatory or nitrosative stress pathways through biomarkers like TNF-, IL-10, TGF-, inducible NO synthase, NO production, protein nitrosylation, and bacterial translocation in ME/CFS patients to better understand their roles [79]

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