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demonstrated that genetic or pharmacological inhibition of the pentose phosphate pathway (PPP) influenced circadian period length in a Nrf2-dependent manner 89

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Changes in -CTX-I and BMD were small and not statistically significant, indicating that short-term supplementation preferentially affects oxidative stress and bone resorption rather than producing immediately detectable effects on bone mass

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Women typically achieve slightly higher percentage weight loss than men, plateau later in treatment, and experience different patterns of fat distribution changes

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