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Unfolding of mucins is dependent on concentrations of bicarbonate, calcium, and sodium in the airway with high concentrations of extracellular calcium, acidic pH, or hyperabsorption of sodium preventing unfolding of the gel-forming mucins (Kesimer et al., 2010

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doi: 10.1006/abbi.1998.0914

PCAC is an advisory committee, and the discussion is about compounding policy, not FDA drug approval

To see if this intestinal fermentation can influence conditions beyond the colon, Trompette and colleagues showed that when mice were fed a high- vs