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This multiscale delivery system, utilizing BMSC differentiation, holds potential for clinical applications in IVD regenerative therapy

Acknowledgments The authors are grateful for the kind support provided by John Poulton, Susan Poulton, and Tabitha J

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In younger cells, FOXO4 appeared to be mostly in the cytoplasm, while in older cells it was more often in the nucleus, which may be considered its more active form