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Similarly, the lipid A components in bacteria from extreme environments can differ appreciably in structure from the norm, and they together with their biosynthetic enzymes are being studied for their potential therapeutic value

A., Ghanta, K

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J Immunol (2011) 186(6):3299303

This is because in the control, some nisin residues no longer form hydrogen bonds with water molecules, but they stay close enough to the water molecules to form contacts, i.e., the lost hydrogen bonds are now counted as contacts

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