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At an IC50 of 24 mol/L, curcumin did not exhibit significant cytotoxicity but reduced ERK1/2 activity, resulting in cell cycle arrest and enhanced apoptosis (Wang et al., 2021)

Concerning the molecular mechanisms implicated in HGF angiogenic role, there is a strong association with the E-twenty-six (Ets) pathway, which is implicated in the regulation of developmental and mitogen signals (Aoki et al., 2000)

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doi: 10.1074/jbc.M411226200 58 PilonGCharbonneauAWhitePJDallairePPerreaultMKapurSet al

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