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These symptoms may also be influenced by tumor development in the digestive tract

However, acute overdoses and long-term treatment can cause hepatotoxicity

Van Geest RJ, Klaassen I, Lesnik-Oberstein SY et al (2013) Vitreous TIMP-1 levels associate with neovascularization and TGF-2 levels but not with fibrosis in the clinical course of proliferative diabetic retinopathy

Another meta-analysis also showed that prolonged treatment with higher doses of NAC (1200 mg/day) prevents exacerbations of COPD, while lower doses (600 mg/day) may be effective only for patients with chronic bronchitis, without COPD and without airway obstruction [57]

However, the existing evidence suggests that AST could be a valuable adjunctive therapy for PD, potentially improving motor symptoms and cognitive function