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Its the cholesterol, stupid

BasuRay, S., Wang, Y., Smagris, E., Cohen, J

If only one source of protein is fed (as with one type of grass hay), your horse will not get sufficient amino acids to stay healthy and peripheral tissues such as skin, hooves, and joints, will show signs of malnutrition

J Mol Med (Berl) 2016

Finally, while PPAR activation is considered necessary and sufficient for adipogenesis in humans and cell culture systems, including mouse models and cell lines such as 3T3-L1, the fundamental mechanisms of adipogenesis are highly conserved across species, including humans

Both adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL), also known as cholesteryl ester hydrolase, are vital in lipolysis and the generation of free fatty acids (FFAs)