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[PubMed] de la Villa P, Kurahashi T, Kaneko A

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It also binds to metal ions like iron and copper, preventing them from generating more harmful radicals

Two patients with type1 diabetes with hypoleptinemia associated with acquired lipodystrophy were administered r-metHuLeptin

Results We demonstrate a developmental perturbation in CCK-expressing excitatory neurons within the mPFC: their density increases sharply in early postnatal life, stabilizes during adolescence, and typically declines in adulthood in wild-type (WT) mice, yet remains persistently elevated in adult KI counterparts

& Nicolas, J