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Metabolic Rewiring: By stopping the conversion of nicotinamide (NAM) into 1-methylnicotinamide (1-MNA), the cell is forced to recycle NAM into NAD+

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We investigated ferroptosis in AML cells and identified its mitochondrial regulation as a therapeutic vulnerability

Regular monitoring of Glutathione Reductase activity is essential for tracking progress and making necessary adjustments to the treatment plan

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