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PMID: 11148652 Vaccaro A.R..: Point of View: Irreducible dislocations of the Cervical Spine

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Association of Hcy-axes with mitochondrial dysfunction Mitochondria are essential for maintaining cellular homeostasis and function, primarily in oxidative phosphorylation (OXPHOS), and for regulation of ion homeostasis, redox potential, lipid metabolism, metabolite synthesis, cell differentiation, immune system, anti-apoptotic, and anti-aging mechanisms [63]

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PloS One 9:e92900 Skipsey M, Cummins I, Andrews CJ, Jepson I, Edwards R (2005) Manipulation of plant tolerance to herbicides through co-ordinated metabolic engineering of a detoxifying glutathione transferase and thiol cosubstrate

Figure 3b shows the time response of APAP protein adducts and ALT in a patient with late NAC treatment (31 h) (Bhattacharyya et al