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Studies have examined NNMT inhibition in relation to cellular methylation balance, NAD metabolism, and broader metabolic signaling pathways

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A shortage can lead to fatigue, tongue swelling, mouth sores, and gray hair

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When B12 is deficient, COMT fails, adrenaline builds up, and the autonomic nervous system is thrown into a state of chaotic overdrive

NNMT is highly expressed in adipose tissue and plays a role in cellular methyldonor economy and nicotinamide processing