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Rutin is a flavonoid found in various plants, has been reported to ameliorate DN by lowering plasma glucose levels and decreasing OS via the Nrf2 signaling pathway (Tian et al., 2016)

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Overcoming the anatomical and physiological barriers in topical eye surface medication using a peptide-decorated polymeric micelle

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doi:10.1016/j.jmb.2009.03.026

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