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Notably, alterations in the binding of AP-1 family members, such as FRA-2 and JUND, were closely linked to increased DNA methylation, suggesting that mutant HTT may disrupt normal transcriptional regulation (212)
It included 45 patients aged 50 to 79, diagnosed with PD for 310 years, showing at least two cardinal signs, including bradykinesia, and a strong response to dopaminergic therapy
S., Vardjan, N., Zorec, R
doi: 10.3389/fimmu.2022.841723, 2 AlagarasuK.KaushalH.ShindeP.KakadeM.ChaudharyU.PadbidriV.et al
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