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CAFFEINE - GENERAL INFORMATION Caffeine (1,3,7-trimethylcanthine or 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione), a well-known purine alkaloid, was described by Gennaro [8] as a white, odorless powder with a slightly bitter taste

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High pressure liquid chromatography and mass spectrum analysis of DNA derived from the RBC of homozygous individuals for the C667T allele showed a positive correlation of DNA methylation and an inverse correlation with plasma homocysteine levels [50,46] was the first to show that folate acts to stabilize the thermolabile enzyme

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In PD, COMT inhibitors, MAOB inhibitors, and dopamine agonists play crucial roles in managing motor symptoms by modulating dopamine levels and function within the basal ganglia [4, 5]

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