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In hypoxia-ischemia (HI) rat model, a manifestation of severe neurological dysfunction, cerebral infarction, cell apoptosis, and notable neuronal loss is concomitant with reduction in COX5a expression

In living cells, the most common initiator of lipid peroxidation is ROS

This does not invalidate the findings but adds a potential source of bias Single-blind only: While the investigator assessing photos was blinded, patients knew whether they received the active serum or saline, which could influence self-reported satisfaction scores No long-term follow-up: The study ended at 6 months

O., Minasian, R

Genchi G, Sinicropi MS, Lauria G, Carocci A, Catalano A

Protective mechanism of Korean Red Ginseng in cisplatin-induced ototoxicity through attenuation of nuclear factor-B and caspase-1 activation