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Increasing Energy Levels Fatigue is one of the most common symptoms of a B12 deficiency

Although expression levels of glycolytic enzymes were not investigated, it was hypothesized that exhausted T cells have an enhanced dependence on glycolysis to counteract mitochondrial dysfunction

The mechanism is scientifically sound and consistently supported by animal data, but human efficacy and safety have not been established through clinical trials

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Dose: Most vitamin B12 supplements contain rather high doses

According to the National Institutes of Health (NIH), no Tolerable Upper Intake Level (UL) has been established for B12, indicating that the risk of harm from high doses is low [*]