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10.1016/j.amepre.2015.05.027 264 SchettinoL.PrietoM.BenedJ

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Hypoxia inhibits senescence and maintains mesenchymal stem cell properties through down-regulation of E2A-p21 by HIF-TWIST

Interestingly, GLS1-knockout CD4(+) T cells exhibited an increase in the proportion of T helper 1 (TH1) cells, which showed excessive effector function and an increase in exhaustion signatures, but in cytotoxic CD8+ T cells in culture with limited glutamine or treated with a glutamine metabolism inhibitor prevented exhaustion, promoted memory-like T cell differentiation and tumor elimination in vivo [89, 90]

Roach T, Nagel M, Brner A, Eberle C, Kranner I (2018) Changes in tocochromanols and glutathione reveal differences in the mechanisms of seed ageing under seedbank conditions and controlled deterioration in barley

A study demonstrated decreased levels of GSH, creatine, and myo-inositol in ME/CFS patients