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Because IM injections send B12 directly into muscle, the vitamin peaks in blood within about an hour, ensuring tissues get what they need

[DOI] [PMC free article] [PubMed] [Google Scholar] 128.Di Zazzo A., Gaudenzi D., Yin J., Coassin M., Fernandes M., Dana R., Bonini S

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Spheroids were allowed to form over 3 days in hSELS medium supplemented with 50% human serum, which was maintained throughout the entire experiment to preserve the physiological environment

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