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There is no established tolerable upper intake level (UL), so even high-dose injections are safe because your system simply eliminates what it cannot use

[10] One practical consideration during NAD+ Injection therapy is the management of NAD+ metabolism by-products

In: StatPearls [Internet] 2020

Systemic side effects may occur in some individuals

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Your dietary habits also influence the frequency and duration of B12 shots
