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Description
Nature 434 , 843850 (2005)
Bonefeld K, Moller S
These agents can raise blood pressure and blood sugar, so can be a problem for those with uncontrolled hypertension or uncontrolled diabetes mellitus
These properties contribute to its favorable oral absorption, metabolic stability sufficient for once-daily dosing, and tissue distribution compatible with reaching GLP-1 receptors in the pancreas, gastrointestinal tract, and central nervous system
34 (ii) that PPs are not mandatory for the development of oral tolerance
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