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In Gram-negative bacterial infections, serum endotoxin measurements provide earlier detection of sepsis than the culture of bacterial pathogens themselves [55, 68]

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While biotin, collagen, and keratin are generally considered safe, dosages in hair growth supplements may exceed standard prenatal recommendations

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Molecular and Cellular Endocrinology , 346 (1), 412
The FDA has cited concerns over the lack of large-scale, randomized, placebo-controlled human trials demonstrating its safety and efficacy