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The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease
Jiang et al., Itaconate attenuates osteoarthritis by inhibiting STING/NF-kappaB axis in chondrocytes and promoting M2 polarization in macrophages
In another research, the chitosan nanoparticles were exploited, because of their hydrophilic nature and cationic properties, which allowed them to cross the BBB and have a high drug entrapment and release efficiency (122)
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Glutathione injections work by delivering a high dose of the antioxidant directly into the muscle
(Yang et al., 2001
