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5 (5), e1230

Biomedicines, 6 (3), 91

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This phenotype was accompanied by accumulation of intracellular ferrous iron and lipid peroxides and the extracellular release of malondialdehyde, all indicative of redox stress, and increased levels of lactate dehydrogenase in the culture supernatant, indicating enhanced cell injury

Importantly, multiple targets do not mean that research related to single chemical metabolites should be ignored in TMMM (Zhao et al., 2018), validated that gut microbiota transformed albiflorin to benzoic acid, which is a key intestinal metabolite that can cross the bloodbrain barrier and inhibit brain D-amino acid oxidase, thereby improving brain function and exerting antidepressant effects

Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer