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While this once-weekly injectable medication effectively improves glycemic control and promotes weight loss, questions have emerged about its potential impact on vitamin B12 levels

Lipid profile effects of omega-3 PUFA are also directly related to activation of FFAR4/GPR120

Traumatic brain injury For decades, preclinical and small clinical studies have investigated the effect of citicoline when provided intravenously, intramuscularly, or orally in the management of traumatic brain injury (TBI)

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Notably, mitochondrial metabolites or TCA cycle enzymes can translocate to the nucleus, where they modulate histone modifications and gene expression, thereby initiating a cascade of retrograde signals that reshape nuclear gene expression and drive cellular reprogramming

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