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In contrast to this, the LBD of subunit A and D undergo a smaller degree of anti-clockwise rotation by ~7.7 and ~17.5 respectively and hence are unable to achieve a dimeric configuration (Fig

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2,3,17,35,36 These conditions are usually managed as per the standard of care and in addition to the treatment of iron overload

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doi: 10.1186/s40478-022-01421-9 279 TristB
